6-Bromo-2-methyl-4-quinolinol

Basic Information

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CAS Number

103030-28-0

Molecular Formula

C10H8BrNO

Molecular Weight

238.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

328.2ºC at 760mmHg

Density

1.523g/cm3

Flash Point

152.3ºC

Refractive Index

1.606

SMILES

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CC1=CC(=O)C2=C(N1)C=CC(=C2)Br

InChI

InChI=1S/C10H8BrNO/c1-6-4-10(13)8-5-7(11)2-3-9(8)12-6/h2-5H,1H3,(H,12,13)

InChIKey

WPSHYKVAGQUPJD-UHFFFAOYSA-N

LogP

3.0113200000000013

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

262

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H318 Causes serious eye damage
Serious eye damage/eye irritation

Synonyms & References

English

Oprea1_255541
4-Quinolinol, 6-bromo-2-methyl-
SMR000122960
103030-28-0
SY227093
Z3220164239
6-bromo-2-methyl-1,4-dihydroquinolin-4-one
EN300-192538
SCHEMBL20605606
HMS1672D22
MFCD00484433
Oprea1_626515
112182-47-5
6-Bromo-2-methyl-quinolin-4-ol
SCHEMBL4966064
6-bromo-2-methyl-4-quinolone
AS-59749
6-bromo-2-methylquinolin-4-ol
AKOS000618449
CS-0091225
5797-35-3
FT-0764959
HMS2384M10
6-bromo-2-methylquinolin-4(1H)-one
6-bromo-2-methyl-4(1H)-quinolinone
6-bromo-2-methyl-1H-quinolin-4-one
CHEMBL1566710
SB71470
6-bromo-4-hydroxyquinaldine
SMSF0007874
VU0509123-1

MDL Number

MFCD00484433

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0)?

6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0) is a brown crystalline solid with a molecular weight of approximately 228.01 g/mol. It has a solubility of about 0.03 g/100 mL in water and is slightly soluble in common organic solvents. The compound is known for its reactivity and can undergo substitution reactions, particularly with nucleophiles at the bromine atom.

How is 6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0) typically synthesized?

6-Bromo-2-methyl-4-quinolinol is typically synthesized through the bromination of 2-methyl-4-quinoline alcohol. This process involves treating the alcohol with bromine in the presence of a base such as sodium hydroxide or potassium hydroxide. The reaction yields the desired compound with high selectivity and moderate to good yield, depending on reaction conditions.

What industries use 6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0)?

6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the synthesis of dyes and pigments, as well as in the production of materials for sensors and semiconductors.

What precautions should be taken when handling 6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0)?

When handling 6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0), wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Use a fume hood to minimize exposure to fumes. Store the compound in a tightly sealed container in a cool, dry place away from direct sunlight. In case of a spill, handle it carefully and follow proper disposal procedures. Refer to the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.