6-Bromo-2-methyl-4-quinolinol(CAS: 103030-28-0)

6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0) is a brown crystalline solid with a molecular weight of approximately 228.01 g/mol. It has a solubility of about 0.03 g/100 mL in water and is slightly soluble in common organic solvents. The compound is known for its reactivity and can undergo substitution reactions, particularly with nucleophiles at the bromine atom.

6-Bromo-2-methyl-4-quinolinol is typically synthesized through the bromination of 2-methyl-4-quinoline alcohol. This process involves treating the alcohol with bromine in the presence of a base such as sodium hydroxide or potassium hydroxide. The reaction yields the desired compound with high selectivity and moderate to good yield, depending on reaction conditions.

6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the synthesis of dyes and pigments, as well as in the production of materials for sensors and semiconductors.

When handling 6-Bromo-2-methyl-4-quinolinol (CAS: 103030-28-0), wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Use a fume hood to minimize exposure to fumes. Store the compound in a tightly sealed container in a cool, dry place away from direct sunlight. In case of a spill, handle it carefully and follow proper disposal procedures. Refer to the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.