1-(4-Nitrophenyl)pyrrolidine

Basic Information

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CAS Number

10220-22-1

Molecular Formula

C10H12N2O2

Molecular Weight

192.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

167-169°C

SMILES

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C1CCN(C1)C2=CC=C(C=C2)[N+](=O)[O-]

InChI

InChI=1S/C10H12N2O2/c13-12(14)10-5-3-9(4-6-10)11-7-1-2-8-11/h3-6H,1-2,7-8H2

InChIKey

IXQSJUBRGIJRCV-UHFFFAOYSA-N

LogP

2.78320

Complexity

201

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

10220-22-1
CS-0205958
FT-0679912
DTXSID40326236
AKOS005069169
1-(4-nitrophenyl)pyrrolidine
Oprea1_361277
AM20060976
N-p-Nitrophenyl-pyrrolidin
IXQSJUBRGIJRCV-UHFFFAOYSA-
10G-310S
EN300-85830
SCHEMBL378458
MFCD00020819
AE-473/30080002
NSC-525710
NSC525710
A18023
InChI=1/C10H12N2O2/c13-12(14)10-5-3-9(4-6-10)11-7-1-2-8-11/h3-6H,1-2,7-8H2
SR-01000473695
SR-01000473695-1
1-{4-nitrophenyl}pyrrolidine
1-(4-Nitro-phenyl)-pyrrolidine
Pyrrolidine,1-(4-nitrophenyl)-
J-503373
IXQSJUBRGIJRCV-UHFFFAOYSA-N
1-(4-Nitrophenyl)pyrrolidine
4-(Pyrrolidin-1-yl)nitrobenzene
1-(Pyrrolidin-1-yl)-4-nitrobenzene

MDL Number

MFCD00020819

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1-(4-Nitrophenyl)pyrrolidine (CAS: 10220-22-1)?

1-(4-Nitrophenyl)pyrrolidine is a white crystalline solid with a molecular weight of approximately 214.11 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is a reactive compound, particularly susceptible to reduction and nitro group substitution reactions.

How is 1-(4-Nitrophenyl)pyrrolidine (CAS: 10220-22-1) typically synthesized?

1-(4-Nitrophenyl)pyrrolidine can be synthesized by reacting 4-nitrophenol with pyrrolidine in the presence of a suitable base like sodium hydroxide. This reaction typically yields a 75-85% yield with good selectivity. The process requires careful control of temperature and reaction time to achieve the desired product.

What industries use 1-(4-Nitrophenyl)pyrrolidine (CAS: 10220-22-1)?

1-(4-Nitrophenyl)pyrrolidine is used in various industries, including pharmaceuticals for its potential as a precursor in drug synthesis, and in polymer chemistry for the modification of polymers. It is also relevant in the semiconductor industry for its use in the fabrication of certain materials.

What precautions should be taken when handling 1-(4-Nitrophenyl)pyrrolidine (CAS: 10220-22-1)?

When handling 1-(4-Nitrophenyl)pyrrolidine, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.