1-(4-Nitrophenyl)pyrrolidine(CAS: 10220-22-1)

1-(4-Nitrophenyl)pyrrolidine is a white crystalline solid with a molecular weight of approximately 214.11 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is a reactive compound, particularly susceptible to reduction and nitro group substitution reactions.

1-(4-Nitrophenyl)pyrrolidine can be synthesized by reacting 4-nitrophenol with pyrrolidine in the presence of a suitable base like sodium hydroxide. This reaction typically yields a 75-85% yield with good selectivity. The process requires careful control of temperature and reaction time to achieve the desired product.

1-(4-Nitrophenyl)pyrrolidine is used in various industries, including pharmaceuticals for its potential as a precursor in drug synthesis, and in polymer chemistry for the modification of polymers. It is also relevant in the semiconductor industry for its use in the fabrication of certain materials.

When handling 1-(4-Nitrophenyl)pyrrolidine, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.