5-Bromo-4-methyl-3-nitro-2-pyridinamine

Basic Information

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CAS Number

100367-40-6

Molecular Formula

C6H6BrN3O2

Molecular Weight

232.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

168.0 to 172.0 deg-C

Boiling Point

314.1℃ at 760 mmHg

Density

1.795

Flash Point

143.8℃

Refractive Index

1.658

SMILES

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CC1=C(C(=NC=C1Br)N)[N+](=O)[O-]

InChI

InChI=1S/C6H6BrN3O2/c1-3-4(7)2-9-6(8)5(3)10(11)12/h2H,1H3,(H2,8,9)

InChIKey

KFVGEPWMVKZPND-UHFFFAOYSA-N

LogP

2.74730

Complexity

184

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

CS-M1656
2-amino-3-nitro-4-methyl-5-bromopyridine
2-PYRIDINAMINE, 5-BROMO-4-METHYL-3-NITRO-
SCHEMBL203339
100367-40-6
BCP23411
KFVGEPWMVKZPND-UHFFFAOYSA-N
AC-23098
2-Amino-5-bromo-3-nitro-4-picoline
A16178
DTXSID40428426
MFCD00092197
FT-0642421
2-amino-5-bromo-3-nitro-4-methyl-pyridine
EN300-134408
Q-103357
SY017447
PB17111
BDBM626019
AKOS007930477
2-Amino-5-bromo-4-methyl-3-nitropyridine
DS-13049
AM20050600
5-bromo-4-methyl-3-nitropyridin-2-amine
2-AMINO-5-BROMO-3-NITRO-4-PICOLINE
2-AMINO-3-NITRO-5-BROMO-4-PICOLINE
2-Amino-5-bromo-3-nitro-GAMMA-picoline
5-bromo-4-methyl-3-nitro-2-Pyridinamine
2-AMINO-3-NITRO-4-METHYL-5-BROMOPYRIDINE
5-bromo-4-methyl-3-nitro-2-pyridylamine
PubChem1234

MDL Number

MFCD00092197

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Bromo-4-methyl-3-nitro-2-pyridinamine (CAS: 100367-40-6)?

5-Bromo-4-methyl-3-nitro-2-pyridinamine is a crystalline solid with a molecular weight of approximately 267.04 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. The compound is known for its high reactivity, particularly towards nucleophilic substitution and reduction reactions.

How is 5-Bromo-4-methyl-3-nitro-2-pyridinamine (CAS: 100367-40-6) typically synthesized?

5-Bromo-4-methyl-3-nitro-2-pyridinamine can be synthesized through a multi-step process involving the nitration of 4-methyl-5-nitro-2-pyridinamine followed by bromination. This typically requires the use of concentrated nitric acid and fuming sulfuric acid, with bromination using N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide.

What industries use 5-Bromo-4-methyl-3-nitro-2-pyridinamine (CAS: 100367-40-6)?

5-Bromo-4-methyl-3-nitro-2-pyridinamine finds applications in the pharmaceutical industry for the synthesis of certain intermediates and in the electronics industry for the production of semiconductors and other materials. It is also used in the development of organic sensors and as a reagent in various chemical processes.

What precautions should be taken when handling 5-Bromo-4-methyl-3-nitro-2-pyridinamine (CAS: 100367-40-6)?

When handling 5-Bromo-4-methyl-3-nitro-2-pyridinamine, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risks. Ensure proper storage in a cool, dry place away from direct sunlight and flammable materials. In the event of a spill, neutralize the compound with water and clean up according to standard laboratory safety protocols.