5-Bromo-4-methyl-3-nitro-2-pyridinamine(CAS: 100367-40-6)

5-Bromo-4-methyl-3-nitro-2-pyridinamine is a crystalline solid with a molecular weight of approximately 267.04 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. The compound is known for its high reactivity, particularly towards nucleophilic substitution and reduction reactions.

5-Bromo-4-methyl-3-nitro-2-pyridinamine can be synthesized through a multi-step process involving the nitration of 4-methyl-5-nitro-2-pyridinamine followed by bromination. This typically requires the use of concentrated nitric acid and fuming sulfuric acid, with bromination using N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide.

5-Bromo-4-methyl-3-nitro-2-pyridinamine finds applications in the pharmaceutical industry for the synthesis of certain intermediates and in the electronics industry for the production of semiconductors and other materials. It is also used in the development of organic sensors and as a reagent in various chemical processes.

When handling 5-Bromo-4-methyl-3-nitro-2-pyridinamine, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risks. Ensure proper storage in a cool, dry place away from direct sunlight and flammable materials. In the event of a spill, neutralize the compound with water and clean up according to standard laboratory safety protocols.