Compound Q&A

How is 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio) (CAS: 147149-76-6) typically synthesized?

Answer

4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-
4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio) can be synthesized using a multi-step process involving the condensation of 2-amino-6-methyl-5-thio-1,4-dihydropyridin-3(2H)-one with 1,3-dibromopropane, followed by reaction with 4-bromopyridine. The process is catalyzed by palladium complexes, and the final product is obtained with good yield and selectivity. Detailed experimental procedures can be found in the literature.

About

English Name 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-
Molecular Formula C14H12N4OS
Molecular Weight 284.34 g/mol
SMILES CC1=C(C2=C(C=C1)N=C(NC2=O)N)SC3=CC=NC=C3
InChIKey XHWRWCSCBDLOLM-UHFFFAOYSA-N
Last Updated: 2026-03-10 19:33

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