4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-(CAS: 147149-76-6)

4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio) is a crystalline solid with a molecular weight of approximately 306.35 g/mol. It is slightly soluble in water and organic solvents. The compound exhibits good stability under normal conditions but can be reactive under certain conditions, particularly at high temperatures or in the presence of strong acids or bases. It is a versatile molecule with potential applications in pharmaceuticals and materials science.

4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio) can be synthesized using a multi-step process involving the condensation of 2-amino-6-methyl-5-thio-1,4-dihydropyridin-3(2H)-one with 1,3-dibromopropane, followed by reaction with 4-bromopyridine. The process is catalyzed by palladium complexes, and the final product is obtained with good yield and selectivity. Detailed experimental procedures can be found in the literature.

4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio) finds applications in the pharmaceutical industry for its potential as a drug candidate. It may also be used in the development of novel materials, particularly in sensors and semiconductors, due to its unique physicochemical properties. Additionally, it can be explored for its potential in polymer synthesis and related applications.

When handling 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio), appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Detailed safety data sheets (SDS) should be consulted for specific handling procedures and emergency response information.