2-Methyl-2-propanyl 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinecarboxylate(CAS: 1698027-20-1)

The compound has a crystalline form with a molecular weight of approximately 532.04 g/mol. It is moderately soluble in common organic solvents like DMSO and acetonitrile. Chemically, it is reactive towards nucleophiles and electrophiles, showing good reactivity under mild conditions. It can form stable complexes with certain metal ions.

This compound is typically synthesized via a multi-step process involving the condensation of 2-methyl-2-propanol with 7-bromo-6-chloro-8-fluoro-4-quinazoline, followed by the coupling of the resulting intermediate with 1-piperazinecarboxylic acid. The reaction is catalyzed by a suitable organic acid and proceeds under mild conditions with high yield.

This compound is primarily used in the pharmaceutical industry for the development of novel drugs. It may also find applications in materials science, specifically in the production of advanced polymers with tailored properties, and in the development of sensors and semiconductors.

When handling this compound, it is essential to wear proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be immediately cleaned up using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and disposal information.