Compound Q&A
How is 2-Methyl-2-propanyl 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinecarboxylate (CAS: 1698027-20-1) typically synthesized?
Answer
This compound is typically synthesized via a multi-step process involving the condensation of 2-methyl-2-propanol with 7-bromo-6-chloro-8-fluoro-4-quinazoline, followed by the coupling of the resulting intermediate with 1-piperazinecarboxylic acid. The reaction is catalyzed by a suitable organic acid and proceeds under mild conditions with high yield.
About
CAS No
1698027-20-1
English Name
2-Methyl-2-propanyl 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinecarboxylate
Molecular Formula
C17H19BrClFN4O2
Molecular Weight
445.72 g/mol
SMILES
CC(C)(C)OC(=O)N1CCN(CC1)C1N=CN=C2C(F)=C(Br)C(Cl)=CC=12
InChIKey
WKUMTSOYOFGRSM-UHFFFAOYSA-N
Last Updated: 2026-03-10 14:55
