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Avapritinib(CAS: 1703793-34-3)
CAS Number
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Basic Information
Molecular Formula
C26H27FN10
Molecular Weight
498.57 g/mol
Chemical Identifiers
SMILES
Cn1cc(cn1)c2cc3c(ncnn3c2)N4CCN(CC4)c5ncc(cn5)[C@@](C)(N)c6ccc(F)cc6
InChIKey
DWYRIWUZIJHQKQ-SANMLTNESA-N
Database References
MDL Number
MFCD31544325
FAQ
Avapritinib is a selective inhibitor of the PDGFRA D842V mutation, used in the treatment of gastrointestinal stromal tumor (GIST) with the PDGFRA D842V mutation and systemic mastocytosis (SM) with one or more mutations in the KIT gene.
Avapritinib is primarily used for treating patients with unresectable or metastatic GIST harboring the PDGFRA D842V mutation and systemic mastocytosis with one or more KIT mutations. It is also being studied for other potential uses in oncology.
Avapritinib is generally considered safe when used as directed. However, it can cause side effects such as diarrhea, nausea, and fatigue. Patients should be monitored for these effects and other potential side effects. Always follow the prescribed dosage and medical advice.
Avapritinib should be stored at room temperature (15-30°C) and protected from light. It should be kept in a tightly closed container and away from moisture and heat to maintain its efficacy and stability.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
Contact Person
Li Li
sales@qingypharma.com