Ingliforib | CAS No. 186392-65-4

Ingliforib

Basic Information

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CAS Number

186392-65-4

Molecular Formula

C23H24ClN3O5

Molecular Weight

457.91 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

843.3°C at 760 mmHg

Density

1.495

Flash Point

463.8°C

Refractive Index

1.712

SMILES

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C1C(C(CN1C(=O)C(C(CC2=CC=CC=C2)NC(=O)C3=CC4=C(N3)C=CC(=C4)Cl)O)O)O

InChI

InChI=1S/C23H24ClN3O5/c24-15-6-7-16-14(9-15)10-18(25-16)22(31)26-17(8-13-4-2-1-3-5-13)21(30)23(32)27-11-19(28)20(29)12-27/h1-7,9-10,17,19-21,25,28-30H,8,11-12H2,(H,26,31)/t17-,19-,20+,21+/m0/s1

InChIKey

GVDRRZOORHCTAN-MJUUVYJYSA-N

LogP

1.0873000000000006

Topological Polar Surface Area

125.89000000000001 Å²

Hydrogen Bond Donor/Acceptor

5 / 8

Complexity

666

Synonyms & References

English

N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxamide
5-chloro-N-[(2S,3R)-4-[(3S,4R)-3,4-dihydroxypyrrolidin-1-yl]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-1H-indole-2-carboxamide
Ingliforib
UII7156WLU
(R-(R*,S*-(cis)))-5-Chloro-N-(3-(3,4-dihydroxy-1-pyrrolidinyl)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl)-1H-indole-2-carboxamide
Ingliforib [USAN:INN]
Ingliforib (USAN/INN)
DSSTox_CID_27252
DSSTox_RID_82211
DSSTox_GSID_47252
cp368296
AMY16882
Tox21_300206
5-chloro-N-[(2S,3R)-4-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-3-hydroxy-4-ox
CP-368,296
UNII-UII7156WLU
SCHEMBL122709
5-Chloro-N-((1S,2R)-3-((3R,4S)-3,4-dihydroxy-1-pyrrolidinyl))-2-hydroxy-3-oxo-1-(phenylmethyl)propyl-1H-indole-2-carboxamide
CHEBI:167777
DTXCID2027252
Ingliforib [USAN]
CHEMBL2104888
INGLIFORIB [INN]
1H-Indole-2-carboxamide, 5-chloro-N-((1S,2R)-3-((3R,4S)-3,4-dihydroxy-1-pyrrolidinyl)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl)-
CP-296
5-CHLORO-N-((2S,3R)-4-((3S,4R)-3,4-DIHYDROXYPYRROLIDIN-1-YL)-3-HYDROXY-4-OXO-1-PHENYLBUTAN-2-YL)-1H-INDOLE-2-CARBOXAMIDE
Q27291096
5-Chloro-N-((2S,3R)-4-((3R,4S)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide
CS-0015497
D77972
D04537

FAQ

What regulatory guidelines apply to Ingliforib (CAS: 186392-65-4)?

Ingliforib (CAS: 186392-65-4) is subject to regulations such as GHS classification, REACH under the European Union, and FDA/EPA requirements. Specific guidelines include safety data sheets (SDS), material safety data sheets (MSDS), and environmental release criteria.

Are there alternatives to Ingliforib in synthesis (CAS: 186392-65-4)?

Alternatives to Ingliforib in synthesis include similar compounds with analogous structures or isomers. Common alternatives might involve substituting Ingliforib with reagents like 5-Fluorouracil or analogs such as uracil derivatives, depending on the specific chemical reaction requirements.

What is the market or research trend for Ingliforib (CAS: 186392-65-4)?

The market trend for Ingliforib (CAS: 186392-65-4) indicates increasing research interest, particularly in its applications in pharmaceuticals and biotechnology. Recent studies focus on its potential as a therapeutic agent, with a growing number of clinical trials exploring its efficacy in cancer treatments and other diseases.

How should waste containing Ingliforib (CAS: 186392-65-4) be handled?

Waste containing Ingliforib (CAS: 186392-65-4) should be collected in appropriate containers and stored separately. Proper incineration or professional waste disposal services should be utilized. Environmental protection precautions include ensuring that disposal methods comply with local and international regulations to minimize environmental impact.