8-(Tributylstannyl)quinoline(CAS: 478282-21-2)

8-(Tributylstannyl)quinoline is a yellow solid with a crystalline form. Its molecular weight is approximately 519.4 g/mol. It is poorly soluble in water but soluble in organic solvents such as ethanol and dichloromethane. Chemically, it is relatively stable but can react with acids, leading to the formation of stannic salts. It is typically stored in a dry, dark place to prevent degradation.

8-(Tributylstannyl)quinoline is typically synthesized via the Grignard reaction, where a quinoline reacts with tributyltin bromide in the presence of a Lewis acid catalyst such as aluminum chloride. The reaction is carried out in an inert solvent like toluene at room temperature. The yield is usually around 70-80%, with good selectivity and purity.

8-(Tributylstannyl)quinoline is used in various industries, particularly in the pharmaceutical and semiconductor industries. It serves as a precursor in the synthesis of functional organic molecules and is used as a ligand in organotin chemistry. It also finds applications in the development of luminescent materials and as a component in certain sensors.

When handling 8-(Tributylstannyl)quinoline, it is crucial to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated fume hood to avoid inhalation. Spills should be cleaned up carefully using absorbent materials and disposed of according to local regulations. It is essential to consult the Safety Data Sheet (SDS) for detailed handling and safety information.