Compound Q&A
How is 8-(Tributylstannyl)quinoline (CAS: 478282-21-2) typically synthesized?
Answer
8-(Tributylstannyl)quinoline is typically synthesized via the Grignard reaction, where a quinoline reacts with tributyltin bromide in the presence of a Lewis acid catalyst such as aluminum chloride. The reaction is carried out in an inert solvent like toluene at room temperature. The yield is usually around 70-80%, with good selectivity and purity.
About
CAS No
478282-21-2
English Name
8-(Tributylstannyl)quinoline
Molecular Formula
C21H33NSn
Molecular Weight
418.21 g/mol
SMILES
CCCC[Sn](CCCC)(CCCC)C1=CC=CC2=C1N=CC=C2
InChIKey
CFXBLYUOIPJSEG-UHFFFAOYSA-N
Last Updated: 2026-03-04 21:35
