Benzyl (3S)-3-amino-1-pyrrolidinecarboxylate hydrochloride (1:1)(CAS: 550378-39-7)

Benzyl (3S)-3-amino-1-pyrrolidinecarboxylate hydrochloride (CAS: 550378-39-7) is a crystalline solid with a molecular weight of approximately 269.9 g/mol. It has a pKa of about 1.8, indicating strong acidity. The compound is soluble in water and ethanol. It is mildly basic and can react with acids to form the corresponding salts. It is used in pharmaceutical and chemical synthesis due to its reactivity and functionality.

Benzyl (3S)-3-amino-1-pyrrolidinecarboxylate hydrochloride (CAS: 550378-39-7) is synthesized through the condensation of benzylamine with 1-pyrrolidinecarboxylic acid in the presence of a suitable base like triethylamine. The reaction is typically carried out in an aqueous medium, followed by the addition of hydrochloric acid to protonate the amine group, yielding the hydrochloride salt. This process ensures high yield and good purity.

Benzyl (3S)-3-amino-1-pyrrolidinecarboxylate hydrochloride (CAS: 550378-39-7) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry for modifying polymer properties and in the analytical sector for sensor applications. Its reactivity and functionality make it a valuable intermediate in chemical synthesis.

When handling Benzyl (3S)-3-amino-1-pyrrolidinecarboxylate hydrochloride (CAS: 550378-39-7), it is important to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from heat sources. Work in a well-ventilated area or a fume hood. In case of a spill, avoid contact with eyes and skin; use appropriate absorbent materials for cleanup and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling guidelines.