(2E)-3-[1-({4-[(Dimethylamino)methyl]phenyl}sulfonyl)-1H-pyrrol-3-yl]-N-hydroxyacrylamide(CAS: 864814-88-0)

(2E)-3-[1-({4-[(Dimethylamino)methyl]phenyl}sulfonyl)-1H-pyrrol-3-yl]-N-hydroxyacrylamide is a crystalline solid with a high molecular weight. It has low aqueous solubility but good solubility in organic solvents. The compound is relatively stable under normal conditions but exhibits reactivity towards nucleophiles. It has a melting point of around 200-210°C and a molecular weight of approximately 500 g/mol.

(2E)-3-[1-({4-[(Dimethylamino)methyl]phenyl}sulfonyl)-1H-pyrrol-3-yl]-N-hydroxyacrylamide is usually synthesized via a multi-step process involving sulfonylation, acylation, and amidation reactions. The synthesis often requires the use of Lewis acids as catalysts and proceeds with high selectivity and yield. Detailed procedures are available in the literature.

(2E)-3-[1-({4-[(Dimethylamino)methyl]phenyl}sulfonyl)-1H-pyrrol-3-yl]-N-hydroxyacrylamide finds applications in the pharmaceutical industry for the development of new drug compounds. It is also used in the polymer industry for improving the properties of polymer materials. Additionally, it has potential uses in sensor technology and semiconductor fabrication due to its chemical functionality.

When handling (2E)-3-[1-({4-[(Dimethylamino)methyl]phenyl}sulfonyl)-1H-pyrrol-3-yl]-N-hydroxyacrylamide, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or inside a fume hood. Spills should be cleaned up with care using appropriate materials, and the Material Safety Data Sheet (MSDS) should be consulted for specific handling and disposal instructions.