N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide

Basic Information

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CAS Number

850664-21-0

Molecular Formula

C29H30N8O5

Molecular Weight

570.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.45

SMILES

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CCn1c2cc(ncc2nc1c3c(non3)N)Oc4cccc(c4)NC(=O)c5ccc(cc5)OCCN6CCOCC6

InChI

InChI=1S/C29H30N8O5/c1-2-37-24-17-25(31-18-23(24)33-28(37)26-27(30)35-42-34-26)41-22-5-3-4-20(16-22)32-29(38)19-6-8-21(9-7-19)40-15-12-36-10-13-39-14-11-36/h3-9,16-18H,2,10-15H2,1H3,(H2,30,35)(H,32,38)

InChIKey

YOVNFNXUCOWYSG-UHFFFAOYSA-N

LogP

3.839000000000002

Topological Polar Surface Area

155.67999999999998 Å²

Hydrogen Bond Donor/Acceptor

3 / 13

Complexity

860

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

GSK 269962A
GSK 269962
GSK 269962A *
N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c] pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide
N-[3-[[2-(4-Aminofurazan-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-[[2-(4-morpholinyl)ethyl]oxy]benzamide
GSK-269962
GSK-269962A
GSK269962A
GSK269962
Aminofurazanyl-azabenzimidazole 6n
N-(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(morpholin-4-yl)ethoxy]benzamide
GSK269962A HCl
Kinome_3843
GSK269962A(GSK269962)
MLS006010261
GTPL8037
BDBM14047
YOVNFNXUCOWYSG-UHFFFAOYSA-N
C29H30N8O5
BCP27824
ABP000268
3703AH
BCP9000742
NCGC00241982-0

MDL Number

MFCD09970310

FAQ

What are the physical and chemical properties of N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide (CAS: 850666-21-0)?

The compound is crystalline at room temperature with a molecular weight of approximately 750 g/mol. It has a high solubility in polar solvents like dimethylformamide (DMF) and acetonitrile. Chemically, it is stable under neutral conditions but can react with strong acids or bases. It shows reactivity towards nucleophiles, potentially undergoing substitution reactions.

How is N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide (CAS: 850666-21-0) typically synthesized?

This compound is synthesized via a multistep process involving the condensation of a 1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl-2-(4-amino-1,2,5-oxadiazol-3-yl) derivative with a morpholine derivative. Key reagents include acetic anhydride, dicyclohexylcarbodiimide (DCC), and triethylamine (TEA). The overall yield is around 70%, with good selectivity for the desired product.

What industries use N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide (CAS: 850666-21-0)?

This compound is primarily used in the pharmaceutical industry due to its biological activity. It has potential applications in drug discovery and development, particularly in the treatment of cancer and inflammation. It may also have uses in sensor technology and as a semiconductor material in electronic devices.

What precautions should be taken when handling N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide (CAS: 850666-21-0)?

Handling this compound should be done in a well-ventilated area with appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide | CAS No. 850664-21-0

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Density

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Safety Information

Hazard Statement

Synonyms & References

English

MDL Number

FAQ

What are the physical and chemical properties of N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide (CAS: 850666-21-0)?

How is N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide (CAS: 850666-21-0) typically synthesized?

What industries use N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide (CAS: 850666-21-0)?

What precautions should be taken when handling N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide (CAS: 850666-21-0)?

Related Compounds

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