Compound Q&A

How is (2E)-3-[1-({4-[(Dimethylamino)methyl]phenyl}sulfonyl)-1H-pyrrol-3-yl]-N-hydroxyacrylamide (CAS: 864814-88-0) typically synthesized?

Answer

(2E)-3-[1-({4-[(Dimethylamino)methyl]phenyl}sulfonyl)-1H-pyrrol-3-yl]-N-hydroxyacrylamide
(2E)-3-[1-({4-[(Dimethylamino)methyl]phenyl}sulfonyl)-1H-pyrrol-3-yl]-N-hydroxyacrylamide is usually synthesized via a multi-step process involving sulfonylation, acylation, and amidation reactions. The synthesis often requires the use of Lewis acids as catalysts and proceeds with high selectivity and yield. Detailed procedures are available in the literature.

About

English Name (2E)-3-[1-({4-[(Dimethylamino)methyl]phenyl}sulfonyl)-1H-pyrrol-3-yl]-N-hydroxyacrylamide
Molecular Formula C16H19N3O4S
Molecular Weight 349.41200000000003 g/mol
SMILES CN(C)Cc1ccc(cc1)S(=O)(=O)n2ccc(c2)/C=C/C(=O)NO
InChIKey FECGNJPYVFEKOD-VMPITWQZSA-N
Last Updated: 2025-11-01 18:55

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