5-Nitroquinolin-3-amine(CAS: 98589-84-5)

5-Nitroquinolin-3-amine (CAS: 98589-84-5) is a crystalline, solid compound with a molecular weight of approximately 216.13 g/mol. It has a pKa of 7.8 and is slightly soluble in water. This compound is known for its reactivity, particularly towards nucleophilic substitution reactions, and it can form stable complexes with metal ions.

5-Nitroquinolin-3-amine is typically synthesized through the reduction of 5-nitroquinoline derivatives using hydrazine hydrate. The reaction proceeds through a condensation followed by an amination step, yielding high selectivity and good yield. Catalysts such as palladium or copper can be employed to enhance the reaction efficiency.

5-Nitroquinolin-3-amine is widely used in the pharmaceutical industry for the synthesis of various bioactive compounds. It is also utilized in the polymer industry for the modification of polymer properties and in semiconductor manufacturing for doping processes. Additionally, it has applications in sensor technology due to its ability to form stable complexes with metal ions.

When handling 5-Nitroquinolin-3-amine (CAS: 98589-84-5), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up with caution, using appropriate absorbent materials. For detailed safety information, refer to the safety data sheet (SDS).