3-(3-chlorophenyl)propanoic acid(CAS: 21640-48-2)

3-(3-chlorophenyl)propanoic acid (CAS: 21640-48-2) is a white to off-white crystalline solid with a molecular weight of 228.63 g/mol. It has a high melting point of 165-167°C and is slightly soluble in water. The compound is reactive towards strong bases and is susceptible to hydrolysis under basic conditions. It is used in the synthesis of pharmaceuticals and as a precursor in organic chemistry.

3-(3-chlorophenyl)propanoic acid is typically synthesized through the reaction of 3-chlorophenyl propyl bromide with potassium carbonate. This process involves the use of a solvent such as acetone. The reaction is carried out under basic conditions, generating a high yield of the desired product with good selectivity.

3-(3-chlorophenyl)propanoic acid is primarily used in the pharmaceutical industry for the synthesis of various drugs. It is also utilized as a precursor in the polymer industry for the production of certain types of polymers. Additionally, it is employed in the sensor industry due to its chemical reactivity and in some semiconductor applications for specific functional groups.

When handling 3-(3-chlorophenyl)propanoic acid (CAS: 21640-48-2), it is essential to use proper personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a fume hood to minimize exposure to airborne particles. In case of spills, they should be cleaned up using appropriate absorbent materials and rinsed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.