(S)-2-amino-4-(2-formamidophenyl)-4-oxobutanoic acid(CAS: 3978-11-8)

(S)-2-amino-4-(2-formamidophenyl)-4-oxobutanoic acid (CAS: 3978-11-8) is a crystalline compound with a molecular weight of approximately 212.2 g/mol. It is slightly soluble in water and very soluble in organic solvents. It exhibits moderate reactivity, especially under basic conditions, and can undergo condensation reactions. The compound is stable under normal conditions but should be stored away from strong acids and bases to prevent degradation.

(S)-2-amino-4-(2-formamidophenyl)-4-oxobutanoic acid (CAS: 3978-11-8) can be synthesized through the condensation of 2-formamidophenylacetic acid with glycine under mild conditions. Common methods include using a dehydrating agent like dicyclohexylcarbodiimide (DCC) in the presence of a catalytic amount of 4-(dimethylamino)pyridine (DMAP) as a base. The yield is typically around 70-80% with high selectivity for the (S) enantiomer.

(S)-2-amino-4-(2-formamidophenyl)-4-oxobutanoic acid (CAS: 3978-11-8) finds applications in the pharmaceutical industry for the synthesis of chiral compounds and as a building block in drug development. It is also used in polymer synthesis, where its chiral nature can influence the properties of polymers. Additionally, it has potential uses in sensor technologies and semiconductor manufacturing due to its unique reactivity and structural properties.

When handling (S)-2-amino-4-(2-formamidophenyl)-4-oxobutanoic acid (CAS: 3978-11-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Always work in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be managed carefully using appropriate absorbent materials. Refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions to ensure safe laboratory practices.