3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile | CAS No. 956485-59-9
3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile
Basic Information
CAS Number
956485-59-9
Molecular Formula
C8H4IN3
Molecular Weight
269.04 g/mol
AD
Basic Physical Properties
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H318
Causes serious eye damage
Serious eye damage/eye irritation
Serious eye damage/eye irritation
Hazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- SB14391
- CS-0082397
- 956485-59-9
- 3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile
- DTXSID20640149
- SCHEMBL19779567
- FT-0678347
- 3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile, AldrichCPR
- A845363
- D74462
- MFCD09763667
- AKOS015853746
- 4-Cyano-3-iodo-7-azaindole
- 3-iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile
MDL Number
MFCD09763667
FAQ
What are the physical and chemical properties of 3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS: 956485-59-9)?
3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile is a crystalline solid with a molecular weight of approximately 275.01 g/mol. It has low solubility in water but is more soluble in organic solvents like dimethyl sulfoxide (DMSO) and acetonitrile. Chemically, it is relatively stable but reactive towards nucleophiles and reducing agents.
How is 3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS: 956485-59-9) typically synthesized?
3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile is usually synthesized via the reaction of 1H-pyrrolo[2,3-b]pyridine-4-carbonitrile with iodine in the presence of a Lewis acid catalyst, such as aluminum chloride (AlCl₃). The yield is typically around 70-80%, with good regioselectivity.
What industries use 3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS: 956485-59-9)?
3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile is primarily used in pharmaceuticals for its potential as a drug candidate. It also finds use in the synthesis of other organic compounds and as a reagent in academic research, particularly in the field of organometallic chemistry and medicinal chemistry.
What precautions should be taken when handling 3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS: 956485-59-9)?
When handling 3-Iodo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile, use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a fume hood to avoid inhalation. In case of a spill, use appropriate containment and clean up procedures as outlined in the Safety Data Sheet (SDS).
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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