2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid(CAS: 108466-89-3)

2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid is a crystalline white solid with a molecular weight of approximately 288.34 g/mol. It has moderate solubility in organic solvents such as ethanol and acetone, and is practically insoluble in water. The compound is reactive towards nucleophiles and can undergo condensation reactions. It is also susceptible to hydrolysis under basic conditions.

2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid is typically synthesized through a multi-step process involving the condensation of 2,2-dimethyl-5-aminopentanal with 3,6-dioxaoctane. The reaction is usually catalyzed by a Lewis acid such as aluminum chloride, with a yield of around 85%. The synthetic route involves careful control of reaction conditions to ensure high selectivity and purity.

2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid finds applications in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also used in the polymer industry as a monomer for the development of new materials with specific properties. Additionally, it plays a role in the production of sensors and semiconductors, where its unique chemical structure can enhance performance characteristics.

When handling 2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a dry, well-ventilated area away from heat and sources of ignition. Spills should be handled with care, and the area should be flushed with water. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.