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2-Nitro-4-(trifluoromethyl)aniline(CAS: 400-98-6)

2-Nitro-4-(trifluoromethyl)aniline
CAS Number

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Basic Information

Molecular Formula
C7H5F3N2O2
Molecular Weight
206.12 g/mol

Physical Properties

Melting Point
106.0 to 109.0 deg-C
Boiling Point
265.6 ℃ at 760 mmHg
Flash Point
114.4°C

Chemical Identifiers

SMILES
C1=CC(=C(C=C1C(F)(F)F)[N+](=O)[O-])N
InChIKey
ATXBGHLILIABGX-UHFFFAOYSA-N

Database References

MDL Number
MFCD00007155
Beilstein Registry Number
650808

FAQ

2-Nitro-4-(trifluoromethyl)aniline has a crystalline form and a molecular weight of approximately 227.03 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is known for its high reactivity, particularly towards nucleophiles and reducing agents.
2-Nitro-4-(trifluoromethyl)aniline is typically synthesized through the nitration of 4-(trifluoromethyl)aniline. This process involves the use of a strong nitration mixture, such as a mixture of nitric acid and sulfuric acid, under controlled conditions to ensure high selectivity and yield.
2-Nitro-4-(trifluoromethyl)aniline is used in the pharmaceutical industry for the synthesis of certain drugs, and in the chemical industry for the production of dyes and other organic compounds. It is also utilized in the sensing and semiconductor industries for specific applications.
When handling 2-Nitro-4-(trifluoromethyl)aniline, it is essential to use personal protective equipment such as gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be managed using appropriate spill kits, and the material safety data sheet (MSDS) should be consulted for detailed safety information.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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