Afatinib (BIBW 2992)(CAS: 850140-72-6)

Afatinib, with the CAS number 850140-72-6, is a small molecule inhibitor used primarily in cancer therapy. It has the chemical formula C20H23N5O and is known for its ability to target the epidermal growth factor receptor (EGFR) family. Afatinib is a potent, irreversible inhibitor that is effective against various types of non-small cell lung cancer (NSCLC) and other cancers with specific genetic mutations.

Afatinib (CAS: 850140-72-6) is mainly used in the treatment of non-small cell lung cancer (NSCLC) and other cancers that have specific mutations in the EGFR gene. It is also employed in research for studying kinase inhibition and in pharmaceutical development as a targeted therapy drug. Its applications extend to clinical trials for various malignancies with EGFR overexpression.

Afatinib (CAS: 850140-72-6) is generally safe when used as prescribed, but it may cause side effects such as diarrhea, rash, and liver toxicity. Proper handling and adherence to safety guidelines are essential to minimize risks. It is approved by regulatory bodies like the FDA and should be used under medical supervision to ensure safe administration.

Afatinib (CAS: 850140-72-6) should be stored in a cool, dry, and dark place, away from moisture and light. It is typically kept at a temperature between 15°C and 25°C. The container should be airtight and properly labeled to maintain stability and prevent contamination.