Compound Q&A

What are the main uses of Afatinib (CAS: 850140-72-6)?

Answer

Afatinib (BIBW 2992)
Afatinib (CAS: 850140-72-6) is mainly used in the treatment of non-small cell lung cancer (NSCLC) and other cancers that have specific mutations in the EGFR gene. It is also employed in research for studying kinase inhibition and in pharmaceutical development as a targeted therapy drug. Its applications extend to clinical trials for various malignancies with EGFR overexpression.

About

English Name Afatinib (BIBW 2992)
Molecular Formula C24H25ClFN5O3
Molecular Weight 485.95 g/mol
SMILES CN(C)CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]4CCOC4
InChIKey ULXXDDBFHOBEHA-CWDCEQMOSA-N
Last Updated: 2025-08-25 01:08

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