Compound Q&A
What is Afatinib (CAS: 850140-72-6)?
Answer
Afatinib, with the CAS number 850140-72-6, is a small molecule inhibitor used primarily in cancer therapy. It has the chemical formula C20H23N5O and is known for its ability to target the epidermal growth factor receptor (EGFR) family. Afatinib is a potent, irreversible inhibitor that is effective against various types of non-small cell lung cancer (NSCLC) and other cancers with specific genetic mutations.
About
CAS No
850140-72-6
English Name
Afatinib (BIBW 2992)
Molecular Formula
C24H25ClFN5O3
Molecular Weight
485.95 g/mol
SMILES
CN(C)CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]4CCOC4
InChIKey
ULXXDDBFHOBEHA-CWDCEQMOSA-N
Last Updated: 2025-08-25 01:08
