Almorexant | CAS No. 871224-64-5

Almorexant

Basic Information

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CAS Number

871224-64-5

Molecular Formula

C29H31F3N2O3

Molecular Weight

512.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.205

SMILES

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CNC(=O)C(N1CCc2c(C1CCc1ccc(cc1)C(F)(F)F)cc(c(c2)OC)OC)c1ccccc1

InChI

InChI=1S/C29H31F3N2O3/c1-33-28(35)27(20-7-5-4-6-8-20)34-16-15-21-17-25(36-2)26(37-3)18-23(21)24(34)14-11-19-9-12-22(13-10-19)29(30,31)32/h4-10,12-13,17-18,24,27H,11,14-16H2,1-3H3,(H,33,35)/t24-,27+/m0/s1

InChIKey

DKMACHNQISHMDN-RPLLCQBOSA-N

LogP

5.7419000000000056

Topological Polar Surface Area

50.80000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Synonyms & References

English

Almorexant
3,4-Dihydro-6,7-dimethoxy-N-methyl-alpha-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-2(1H)-isoquinolineacetamide
(R)-2-((R)-6,7-dimethoxy-1-(4-(trifluoromethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide
(2R)-2-((1S)-6,7-Dimethoxy-1-{2-(4-(trifluoromethyl)phenyl)ethyl}-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide
(2R)-2-{(1S)-6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-3,4-dihydro-1H-isoquinolin-2-yl}-N-methyl-2-phenyl-acetamide
(R)-2-{(S)-6,7-dimethoxy-1-[2-(4-trifluoromethylphenyl)ethyl]-3,4-dihydro-1H-isoquinolin-2-yl}-N-methyl-2-phenylacetamide
[3H]-Almorexant
ACT 078573
ACT-078573
Almorexant [inn]
AlMorexant HCl
Almorexant-13C,D3
(R)-2-((S)-6,7-dimethoxy-1-(4-(trifluoromethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide

MDL Number

MFCD22419385

FAQ

What is Almorexant (CAS: 871224-64-5)?

Almorexant is a novel sleep-promoting compound used in the treatment of insomnia. It is a dual orexin receptor antagonist with high selectivity for the orexin-2 receptor. Almorexant has a molecular formula of C22H27FN4O and is characterized by its ability to modulate the activity of orexinergic pathways in the brain.

What are the main uses of Almorexant (CAS: 871224-64-5)?

Almorexant (CAS: 871224-64-5) is primarily used for the treatment of insomnia. It is effective in promoting sleep onset and maintaining sleep continuity. The drug has been developed to provide a safer alternative to traditional sedatives, with fewer side effects and a lower risk of dependence.

Is Almorexant (CAS: 871224-64-5) safe?

Almorexant (CAS: 871224-64-5) is considered safe when used under the guidance of a healthcare professional. It has been evaluated for potential side effects and has a lower risk of dependency compared to other sleep aids. However, like any medication, it requires appropriate monitoring and adherence to prescribed dosages to ensure safety.

How should Almorexant (CAS: 871224-64-5) be stored?

Almorexant (CAS: 871224-64-5) should be stored in a cool, dry place, away from direct sunlight and heat. It should be kept out of reach of children and pets. It is advisable to store the medication in its original container to maintain its integrity and prevent exposure to moisture and light. Proper storage is crucial to ensure the effectiveness and safety of the drug.