Odanacatib | CAS No. 603139-19-1

Odanacatib

Basic Information

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CAS Number

603139-19-1

Molecular Formula

C25H27F4N3O3S

Molecular Weight

17.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

681.6±55.0°C at 760 mmHg

Density

1.35

SMILES

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CC(C)(CC(C(=O)NC1(CC1)C#N)NC(C2=CC=C(C=C2)C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F

InChI

InChI=1S/H3N/h1H3

InChIKey

QGZKDVFQNNGYKY-UHFFFAOYSA-N

LogP

0.16199999999999998

Topological Polar Surface Area

35.0 Å²

Hydrogen Bond Donor/Acceptor

3 / 1

Complexity

934

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-(((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)pentanamide
Odanacatib (MK 0822)
MK-0822A
N-(1-Cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl}-L-leucinamide
NS00072488
MK-0822;MK 0822;MK0822
ODANACATIB [MI]
J-690332
EX-A552
BDBM50255753
NSC766811
SMR004676504
MK-0822
Odanacatib (MK0822)
cas:603139-19-1;Odanacatib
AKOS015900719
BCPP000141
(2S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4-(4-methylsulfonylphenyl)phenyl]ethyl]amino]pentanamide
Odanacatib (JAN/USAN)
MFCD11042419
N673F6W2VH
N1-(1-cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)-1,1'-biphenyl-4-yl]ethyl}-L-leucinamide
CCG-269888
DTXSID40209075
NSC-766811
SW219669-1
DB06670
MK0822
Pentanamide, N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-(((1S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)(1,1'-biphenyl)-4-yl)ethyl)amino)-, (2S)-
L-1037536
603139-19-1

MDL Number

MFCD11042419

FAQ

What regulatory guidelines apply to Odanacatib (CAS: 603139-19-1)?

Odanacatib (CAS: 603139-19-1) falls under the purview of various regulatory guidelines such as the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations in the European Union, and the regulatory requirements of the FDA and EPA in the United States. Manufacturers and distributors must ensure compliance with these guidelines for labeling, storage, and transportation.

Are there alternatives to Odanacatib (CAS: 603139-19-1) in synthesis?

Yes, there are alternative reagents and synthetic pathways for Odanacatib (CAS: 603139-19-1). For instance, other cathepsin K inhibitors like ONO-5334 or TLK286 can be used as alternatives. These alternatives may offer similar or enhanced properties depending on the specific requirements of the synthesis.

What is the market or research trend for Odanacatib (CAS: 603139-19-1)?

The market trend for Odanacatib (CAS: 603139-19-1) is positive, driven by its potential in the treatment of osteoporosis. Research is focusing on better understanding its pharmacodynamics, improving its bioavailability, and exploring its use in combination therapies. Additionally, there is growing interest in its use for bone turnover markers in clinical diagnostics.

How should waste containing Odanacatib (CAS: 603139-19-1) be handled?

Waste containing Odanacatib (CAS: 603139-19-1) should be collected in appropriate containers and stored in a controlled environment to prevent degradation. It should then be disposed of through a professional waste disposal company that follows the regulatory guidelines for hazardous waste management. Environmental protection measures such as minimizing waste generation and recycling wherever possible should also be considered.