2-(4-Methyl-2-phenyl-1-piperazinyl)nicotinic acid(CAS: 61338-13-4)

2-(4-Methyl-2-phenyl-1-piperazinyl)nicotinic acid (CAS: 61338-13-4) is a crystalline compound with a molecular weight of approximately 315.36 g/mol. It has a solubility of about 2.5 mg/mL in water and is slightly soluble in ethanol. The compound is relatively stable under normal conditions, but it can undergo hydrolysis under basic conditions. It shows moderate reactivity with primary amines and nucleophiles.

2-(4-Methyl-2-phenyl-1-piperazinyl)nicotinic acid (CAS: 61338-13-4) can be synthesized through esterification of 2-(4-methyl-2-phenyl-1-piperazinyl)isonicotinic acid with acetic anhydride. The reaction is typically conducted in the presence of a catalytic amount of an acid like sulfuric acid. The yield is usually around 85-90%, with the product being isolated by recrystallization from ethanol.

2-(4-Methyl-2-phenyl-1-piperazinyl)nicotinic acid (CAS: 61338-13-4) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs, particularly those involving piperazine derivatives. It is also utilized in the production of certain polymers, sensors, and semiconductors for their unique chemical properties.

When handling 2-(4-Methyl-2-phenyl-1-piperazinyl)nicotinic acid (CAS: 61338-13-4), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be neutralized with an appropriate base before disposal. Always consult the Safety Data Sheet (SDS) for specific handling and disposal information.