Compound Q&A
How is 2-(4-Methyl-2-phenyl-1-piperazinyl)nicotinic acid (CAS: 61338-13-4) typically synthesized?
Answer
2-(4-Methyl-2-phenyl-1-piperazinyl)nicotinic acid (CAS: 61338-13-4) can be synthesized through esterification of 2-(4-methyl-2-phenyl-1-piperazinyl)isonicotinic acid with acetic anhydride. The reaction is typically conducted in the presence of a catalytic amount of an acid like sulfuric acid. The yield is usually around 85-90%, with the product being isolated by recrystallization from ethanol.
About
CAS No
61338-13-4
English Name
2-(4-Methyl-2-phenyl-1-piperazinyl)nicotinic acid
Molecular Formula
C17H19N3O2
Molecular Weight
297.36 g/mol
SMILES
CN1CCN(C(C1)C1=CC=CC=C1)C1=C(C=CC=N1)C(O)=O
InChIKey
HCVDLMUVEGPGGH-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36
