2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine(CAS: 501-75-7)

2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine is a white crystalline solid with a molecular weight of approximately 147.18 g/mol. It is sparingly soluble in water and ethanol. The compound shows moderate reactivity with weak acids and bases. It has a pKa of around 10.5.

2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine is typically synthesized via a multistep process involving the condensation of 1-methylimidazole with ethylene diamine followed by subsequent reactions to introduce the amine group. Common solvents include methanol and ethanol, and the reaction is usually carried out at room temperature with mild base catalysis.

2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the polymer industry as a stabilizer and in sensor technology due to its unique chemical properties.

When handling 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine, it is recommended to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with appropriate absorbent materials, and the area should be thoroughly rinsed. For detailed safety information, refer to the Material Safety Data Sheet (MSDS/SDS).