2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine

Basic Information

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CAS Number

501-75-7

Molecular Formula

C6H11N3

Molecular Weight

125.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CN1C=C(N=C1)CCN

InChI

InChI=1S/C6H11N3/c1-9-4-6(2-3-7)8-5-9/h4-5H,2-3,7H2,1H3

InChIKey

FHQDWPCFSJMNCT-UHFFFAOYSA-N

LogP

-0.0787000000000001

Topological Polar Surface Area

43.84 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

84.4

Synonyms & References

English

1-methyl-4-(b-aminoethyl)imidazole
GTPL1242
2-(1-Methylimidazole-4-yl)ethanamine
N1-Methylhistamine
HY-W062542
2-(1-methylimidazol-4-yl)ethanamine
NCGC00162240-01
NCGC00015677-02
Lopac0_000757
NCGC00015677-04
N-Telle-methylhistamine
AS-50436
N(sup 1)-Methylhistamine
BRN 0110757
FT-0701318
2-(1-Methyl-1H-imidazol-4-yl)ethylamine
C05127
Tele-methylhistamine
N-[3H]methylhistamine
N.tau.-Methylhistamine
5-25-09-00527 (Beilstein Handbook Reference)
NSC66736
Ntau-Methylhistamine
CHEMBL507
AKOS006350836
Histamine, 1-methyl-
DTXSID30198207
MFCD01941538
N-tele-Methylhistamine
N( 1)-Methylhistamine
UNII-KCB81T4EOF

MDL Number

MFCD01941538

Customs Code

2933290090

FAQ

What are the physical and chemical properties of 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine (CAS: 501-75-7)?

2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine is a white crystalline solid with a molecular weight of approximately 147.18 g/mol. It is sparingly soluble in water and ethanol. The compound shows moderate reactivity with weak acids and bases. It has a pKa of around 10.5.

How is 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine (CAS: 501-75-7) typically synthesized?

2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine is typically synthesized via a multistep process involving the condensation of 1-methylimidazole with ethylene diamine followed by subsequent reactions to introduce the amine group. Common solvents include methanol and ethanol, and the reaction is usually carried out at room temperature with mild base catalysis.

What industries use 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine (CAS: 501-75-7)?

2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the polymer industry as a stabilizer and in sensor technology due to its unique chemical properties.

What precautions should be taken when handling 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine (CAS: 501-75-7)?

When handling 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine, it is recommended to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with appropriate absorbent materials, and the area should be thoroughly rinsed. For detailed safety information, refer to the Material Safety Data Sheet (MSDS/SDS).