(3,5-Difluoro-4-formylphenyl)boronic acid(CAS: 870718-11-9)

(3,5-Difluoro-4-formylphenyl)boronic acid is a white crystalline solid with a molecular weight of approximately 217.10 g/mol. It has a low solubility in water but is more soluble in organic solvents. It is relatively stable under normal conditions but can exhibit reactivity with reducing agents. This compound is commonly used in organic synthesis and as a precatalyst in various reactions.

(3,5-Difluoro-4-formylphenyl)boronic acid is usually synthesized through the bromination of 3,5-difluorophenol followed by the addition of boron tribromide and subsequent hydrolysis. This method provides good yield and selectivity. Alternative routes involve the use of other reagents like boronic acids or esters, depending on the desired purity and reactivity of the final product.

(3,5-Difluoro-4-formylphenyl)boronic acid finds applications in the pharmaceutical industry for the synthesis of medicinal compounds, in the semiconductor industry for the fabrication of electronic materials, and in the polymer industry for the development of functional polymers. It is also used in analytical chemistry for sensing applications.

When handling (3,5-Difluoro-4-formylphenyl)boronic acid, it is essential to wear appropriate personal protective equipment, such as gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up with caution, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures.