2-Fluoro-4-methyl-3-nitropyridine(CAS: 19346-43-1)

2-Fluoro-4-methyl-3-nitropyridine is a crystalline solid with a molecular weight of approximately 196.04 g/mol. It has limited water solubility and is soluble in organic solvents such as ethanol and acetone. It is known for its significant reactivity, particularly towards reduction and hydrolysis reactions.

2-Fluoro-4-methyl-3-nitropyridine is synthesized through a series of reactions including nitration of 4-methyl-3-pyridine carboxylic acid, followed by fluorination. Common catalysts include sulfuric acid for nitration and hydrogen fluoride for fluorination. The yield is around 70-80%.

2-Fluoro-4-methyl-3-nitropyridine is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also has applications in the development of polymers and sensors due to its unique chemical properties.

When handling 2-Fluoro-4-methyl-3-nitropyridine, it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. It should be handled in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for specific handling and storage guidelines.