2,3-Difluoroaniline

Basic Information

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CAS Number

4519-40-8

Molecular Formula

C6H5F2N

Molecular Weight

129.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

69°C/12mmHg

Refractive Index

n20/D 1.514(lit.)

SMILES

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C1=CC(=C(C(=C1)F)F)N

InChI

InChI=1S/C6H5F2N/c7-4-2-1-3-5(9)6(4)8/h1-3H,9H2

InChIKey

YCCQGFYAVUTQFK-UHFFFAOYSA-N

LogP

1.547

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

97.1

Safety Information

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GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

SCHEMBL59477
AC-2725
F0001-1224
AKOS005259161
2,3-difluorophenylamine
SY002696
NS00045821
2,3-difluorobenzenamine
EINECS 224-847-2
2,3-Difluoro-phenylamine
YCCQGFYAVUTQFK-UHFFFAOYSA-
W-106160
BCP10332
PS-9154
FT-0609609
MFCD00010298
Benzenamine, 2,3-difluoro-
2,3-difluorophenyl amine
CS-W007344
DTXSID80196415
D2595
2,3-Difluoroaniline, 98%
difluoraniline
InChI=1/C6H5F2N/c7-4-2-1-3-5(9)6(4)8/h1-3H,9H2
BIDD:GT0108
EN300-52525
Z755885564
4519-40-8
AM61537
2,3-Difluoroaniline
2.3-Difluoroaniline

MDL Number

MFCD00010298

Customs Code

2921420090

FAQ

What are the physical and chemical properties of 2,3-Difluoroaniline (CAS: 4519-40-8)?

2,3-Difluoroaniline is a colorless or white crystalline solid with a molecular weight of approximately 154.01 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it reacts with bases to form anilinium salts and is used in making dyes and pharmaceuticals. It is also used in the synthesis of herbicides and flame retardants.

How is 2,3-Difluoroaniline (CAS: 4519-40-8) typically synthesized?

2,3-Difluoroaniline is typically synthesized via the reduction of 2,3-difluorophenyl isocyanate or by the reaction of 2,3-difluorophenyl methyl ketone with ammonia. The reaction conditions include the use of a suitable reducing agent and a catalyst, which can enhance the yield and selectivity of the product.

What industries use 2,3-Difluoroaniline (CAS: 4519-40-8)?

2,3-Difluoroaniline is used in various industries, including pharmaceuticals, where it serves as a precursor to medications; in the synthesis of herbicides; and in the production of dyes and other organic compounds. It also finds applications in the manufacturing of flame retardants and as a reagent in semiconductor and sensor technologies.

What precautions should be taken when handling 2,3-Difluoroaniline (CAS: 4519-40-8)?

When handling 2,3-Difluoroaniline, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate chemical waste disposal methods, and the Material Safety Data Sheet (MSDS) should be consulted for detailed safety information.