Ethyl 4-amino-2-methylbenzoate(CAS: 74450-59-2)

Ethyl 4-amino-2-methylbenzoate (CAS: 74450-59-2) is a white, crystalline solid with a molecular weight of approximately 219.22 g/mol. It has a solubility of about 12.8 g/L in water and is relatively stable under normal conditions. The compound is slightly acidic and can react with strong bases to form its conjugate base. It is insoluble in water but soluble in organic solvents like ethanol and acetonitrile.

Ethyl 4-amino-2-methylbenzoate (CAS: 74450-59-2) is synthesized through a multi-step process that begins with the reaction of 4-amino-2-methylbenzoic acid with ethyl chloroformate in the presence of a base like triethylamine. The reaction yields the ethyl ester as a primary product with good selectivity and yield. Commonly used solvents include dichloromethane or acetonitrile, and the reaction is typically conducted at room temperature.

Ethyl 4-amino-2-methylbenzoate (CAS: 74450-59-2) is used in various industries due to its chemical properties. It finds applications in the pharmaceutical and chemical industries as a starting material for the synthesis of other compounds. Additionally, it is used in the preparation of certain dyes, pigments, and in the development of organic electronic materials for semiconductors and sensors.

When handling Ethyl 4-amino-2-methylbenzoate (CAS: 74450-59-2), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a fume hood to minimize inhalation risks. Spills should be handled carefully, and the area should be well-ventilated. In case of skin contact, wash the affected area with water. For more detailed safety information, consult the Safety Data Sheet (SDS).