(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(CAS: 16321-99-6)

This compound is an optically active diacetate derivative of 2-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran. It crystallizes in the form of white needles or fine crystals. The molecular weight is approximately 467.31 g/mol. It is poorly soluble in water but soluble in organic solvents like methanol and acetonitrile. The compound exhibits reactivity typical of acyl groups and amine functionalities, making it suitable for various synthetic transformations.

This compound can be synthesized via the condensation of 2-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran with acetic anhydride. Commonly, this is catalyzed by a tertiary amine base such as triethylamine. The reaction typically proceeds with high yield and good selectivity, providing a diacetate product.

This compound is primarily used in the pharmaceutical industry for its potential as a bioactive molecule with possible therapeutic applications. It may also find utility in the synthesis of other complex organic compounds, particularly those involving purine derivatives, which are important in drug development and molecular biology research.

When handling this compound, it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Store the compound in a well-ventilated area and use a fume hood during handling or synthesis. In the event of a spill, immediately clean up using appropriate absorbent materials and follow proper disposal protocols as outlined in the Safety Data Sheet (SDS).