2-(4-Bromophenyl)-2-oxoacetaldehyde hydrate(CAS: 80352-42-7)

2-(4-Bromophenyl)-2-oxoacetaldehyde hydrate (CAS: 80352-42-7) is a white crystalline solid with a molecular weight of approximately 240.02 g/mol. It has a low solubility in water (0.1 g/100 mL at 25°C) and is relatively stable under normal conditions. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is typically stored at room temperature and should be protected from moisture.

2-(4-Bromophenyl)-2-oxoacetaldehyde hydrate (CAS: 80352-42-7) is usually synthesized via the bromination of phenylacetaldehyde followed by acetylation and hydration. The reaction typically involves the use of bromine and a base as a catalyst. The yield is around 70-80% with high selectivity to the desired product.

2-(4-Bromophenyl)-2-oxoacetaldehyde hydrate (CAS: 80352-42-7) is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drugs and intermediates. It also finds applications in the polymer industry for the production of functionalized polymers and in the electronics industry for the development of semiconductors and sensors.

When handling 2-(4-Bromophenyl)-2-oxoacetaldehyde hydrate (CAS: 80352-42-7), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be ventilated thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.