2-Hydroxy-4-quinolinecarboxylic acid

Basic Information

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CAS Number

84906-81-0

Molecular Formula

C10H7NO3

Molecular Weight

189.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

>300 °C

SMILES

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Oc1nc2ccccc2c(c1)C(=O)O

InChI

InChI=1S/C10H7NO3/c12-9-5-7(10(13)14)6-3-1-2-4-8(6)11-9/h1-5H,(H,11,12)(H,13,14)

InChIKey

MFSHNFBQNVGXJX-UHFFFAOYSA-N

LogP

1.6385999999999998

Topological Polar Surface Area

70.42 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

309

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

2-Hydroxyquinoline-4-carboxylic acid
4-Carboxy-2-hydroxyquinoline
2-oxo-1,2-dihydroquinoline-4-carboxylic acid
2-Hydroxycinchoninic acid
2-Hydroxy-4-quinolincarboxylic acid
4-Carboxycarbostyril
4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-
Cinchoninic acid, 2-hydroxy-
1,2-Dihydro-2-oxoquinoline-4-carboxylic acid
2-oxocinchoninic acid
2-oxo-1H-quinoline-4-carboxylic acid
2-Hydroxy-quinoline-4-carboxylic acid
2-hydroxy-4-quinolinecarboxylic acid
4-Quinolinecarboxylic acid, 2-hydroxy-
2-H

MDL Number

MFCD02179738

FAQ

What regulatory guidelines apply to 2-Hydroxy-4-quinolinecarboxylic acid (CAS: 84906-81-0)?

2-Hydroxy-4-quinolinecarboxylic acid (CAS: 84906-81-0) falls under various regulatory guidelines such as GHS (Global Harmonized System of Classification and Labeling of Chemicals) for hazardous substance classification. It is also subject to REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) regulations in the European Union. In the USA, it is regulated by the FDA (Food and Drug Administration) for pharmaceutical use and by the EPA (Environmental Protection Agency) for environmental protection and disposal. Accurate handling and storage are required to comply with these regulations.

Are there alternatives to 2-Hydroxy-4-quinolinecarboxylic acid (CAS: 84906-81-0) in synthesis?

While 2-Hydroxy-4-quinolinecarboxylic acid (CAS: 84906-81-0) is a key compound for certain applications, alternatives such as other quinoline carboxylic acids or their derivatives can be used depending on the specific requirements of the synthesis. Isomers and analogs can also serve as viable substitutes. Common alternatives include 4-Methoxyquinoline-2-carboxylic acid and 4-Chloroquinoline-2-carboxylic acid, which offer similar functionalities with varying reactivity and selectivity.

What is the market or research trend for 2-Hydroxy-4-quinolinecarboxylic acid (CAS: 84906-81-0)?

The market for 2-Hydroxy-4-quinolinecarboxylic acid (CAS: 84906-81-0) is driven by its applications in pharmaceuticals, agrochemicals, and research. Recent trends indicate an increasing demand in the development of new drugs and agrochemicals, contributing to the growth of this market. Research is focused on exploring its potential in drug discovery, particularly in treating neurological disorders and as an herbicide. Additionally, there is growing interest in its biodegradability and environmental impact, which could influence future research and development trends.

How should waste containing 2-Hydroxy-4-quinolinecarboxylic acid (CAS: 84906-81-0) be handled?

Waste containing 2-Hydroxy-4-quinolinecarboxylic acid (CAS: 84906-81-0) should be collected in appropriate containers and stored in a sealed, well-ventilated area. For safe disposal, incineration is recommended, but professional waste disposal services are suggested due to its hazardous nature. Environmental protection measures include ensuring no runoff into water sources and proper documentation of the waste disposal process. Compliance with local and international regulations is essential for safe and responsible waste management.