Tizanidine hydrochloride(CAS: 64461-82-1)

Tizanidine hydrochloride is a white or almost white crystalline powder with a molecular weight of approximately 250.79 g/mol. It is slightly soluble in water and practically insoluble in ethanol. This compound is not very reactive under normal conditions but can be hydrolyzed under basic conditions. The CAS number is 64461-82-1.

Tizanidine hydrochloride is usually synthesized via a multi-step process starting from 6-methyl-6-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid. The key steps include condensation, reduction, and finally conversion to hydrochloride salt. The yield is typically around 85-90%, and the process requires careful control of pH and temperature. The CAS number is 64461-82-1.

Tizanidine hydrochloride is primarily used in the pharmaceutical industry as a muscle relaxant. It is also applicable in the medical field for the treatment of neuropathic pain and hypertension. The CAS number is 64461-82-1.

When handling Tizanidine hydrochloride, it is important to wear appropriate personal protective equipment such as gloves and safety glasses. Ensure the work is conducted in a well-ventilated area or a fume hood. In case of a spill, neutralize the acid with a base and dispose of according to local regulations. Always refer to the safety data sheet (SDS) for detailed precautions. The CAS number is 64461-82-1.