Gliclazide | CAS No. 21187-98-4

Gliclazide

Basic Information

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CAS Number

21187-98-4

Molecular Formula

C15H21N3O3S

Molecular Weight

323.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

163-169 °C

Solubility

methylene chloride: soluble

Refractive Index

1.6740 (estimate)

SMILES

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Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2

InChI

InChI=1S/C15H21N3O3S/c1-11-5-7-14(8-6-11)22(20,21)17-15(19)16-18-9-12-3-2-4-13(12)10-18/h5-8,12-13H,2-4,9-10H2,1H3,(H2,16,17,19)

InChIKey

BOVGTQGAOIONJV-UHFFFAOYSA-N

LogP

1.6298200000000003

Topological Polar Surface Area

78.50999999999999 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

497

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Toxicity

LD50 orally in mice: >3 g/kg (Duhault)

Synonyms & References

English

Gliclazide
BENZENESULFONAMIDE, N-[[(HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL)AMINO]CARBONYL]-4-METHYL
GLIMICRON
DIAMICRON
1-(3-azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea
1-(3-AZABICYGCLO[33.0]OCT-3-YL)-3-O-TOLYLSULPHONYLUREA
AKOS NCG1-0056
N-[[[HEXAHYDROCYLOPENTA[C]PYRROL-2(1H)-YL]AMINO]CARBONYL]-4-METHYLBENZENESULFONAMIDE
GLICLAZIDE USP
1-[3-Azabicyclo[3.3.0]oct-3-yl]-3-p-toluenesulfonylurea
Diaprel
Glinormax
Glyzide
NORDIALEX
S1702
S-1702
s852
se1702
Gliclazida
Gliclazidum [INN-Latin]
Gliclazida [INN-Spanish]
1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea
C15H21N3O3S
1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea
Gliclazidum
N-(hexahydrocyclopenta[c]pyrrol-2(1H)-ylcarbamoyl)-4-methylbenzenesulfonamide
N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea
1-(3,3a,4,5,6,6a-he
N-((hexahydrocyclopenta[c]pyrrol-2(1H)-yl)carbamoyl)-4-methylbenzenesulfonamide

MDL Number

MFCD00409893

Customs Code

2935009090

FAQ

What is Gliclazide (CAS: 21187-98-4)?

Gliclazide is a chemical compound with the CAS number 21187-98-4. It is a derivative of thiazolidinedione and is primarily known for its use as an oral antidiabetic medication. Gliclazide has a molecular formula of C11H12N2O3S and is characterized by its ability to improve insulin sensitivity and lower blood glucose levels in patients with type 2 diabetes.

What are the main uses of Gliclazide (CAS: 21187-98-4)?

Gliclazide is mainly used in the treatment of type 2 diabetes to help regulate blood sugar levels. It works by increasing the body's sensitivity to insulin, thereby enhancing glucose uptake. Additionally, it is used in research settings to study metabolic disorders and has potential applications in pharmaceutical development for diabetes management.

Is Gliclazide (CAS: 21187-98-4) safe?

Gliclazide is generally considered safe when used as directed under medical supervision. However, like all medications, it may have side effects such as hypoglycemia, weight gain, or gastrointestinal discomfort. Proper handling and adherence to safety guidelines are essential to minimize risks. It is approved by regulatory bodies for therapeutic use and meets safety standards in pharmaceutical formulations.

How should Gliclazide (CAS: 21187-98-4) be stored?

Gliclazide should be stored in a cool, dry place, away from light and moisture. It is typically kept in a sealed container at a temperature between 15°C and 30°C. Proper storage ensures stability and prevents degradation, maintaining its efficacy and safety for use in diabetes treatment.