Compound Q&A

How is Tizanidine hydrochloride (CAS: 64461-82-1) typically synthesized?

Answer

Tizanidine hydrochloride
Tizanidine hydrochloride is usually synthesized via a multi-step process starting from 6-methyl-6-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid. The key steps include condensation, reduction, and finally conversion to hydrochloride salt. The yield is typically around 85-90%, and the process requires careful control of pH and temperature. The CAS number is 64461-82-1.

About

CAS No 64461-82-1
English Name Tizanidine hydrochloride
Molecular Formula C9H9Cl2N5S
Molecular Weight 290.18 g/mol
SMILES C1CN=C(N1)NC2=C(C=CC3=NSN=C32)Cl.Cl
InChIKey ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43

Related Q&A

Compound Q&A

What are the physical and chemical properties of Tizanidine hydrochloride (CAS: 64461-82-1)?

Tizanidine hydrochloride is a white or almost white crystalline powder with a molecular weight of ap...

Compound Q&A

What industries use Tizanidine hydrochloride (CAS: 64461-82-1)?

Tizanidine hydrochloride is primarily used in the pharmaceutical industry as a muscle relaxant. It i...

Compound Q&A

What precautions should be taken when handling Tizanidine hydrochloride (CAS: 64461-82-1)?

When handling Tizanidine hydrochloride, it is important to wear appropriate personal protective equi...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...