Angiotensin I (1-7) | CAS No. 51833-78-4

Angiotensin I (1-7)

Basic Information

CAS Number

51833-78-4

Molecular Formula

C41H62N12O11

Molecular Weight

899.02 g/mol

AD

Basic Physical Properties

CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N

InChI

InChI=1S/C41H62N12O11/c1-5-22(4)33(38(61)50-29(17-24-19-45-20-47-24)39(62)53-15-7-9-30(53)40(63)64)52-36(59)28(16-23-10-12-25(54)13-11-23)49-37(60)32(21(2)3)51-35(58)27(8-6-14-46-41(43)44)48-34(57)26(42)18-31(55)56/h10-13,19-22,26-30,32-33,54H,5-9,14-18,42H2,1-4H3,(H,45,47)(H,48,57)(H,49,60)(H,50,61)(H,51,58)(H,52,59)(H,55,56)(H,63,64)(H4,43,44,46)/t22-,26-,27-,28-,29-,30-,32-,33-/m0/s1

InChIKey

PVHLMTREZMEJCG-GDTLVBQBSA-N

LogP

-1.832530000000001

Topological Polar Surface Area

377.23999999999995 Ų

Hydrogen Bond Donor/Acceptor

15 / 23

Complexity

1660

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-proline
  • CS-3413
  • Angiotensin peptide (1-7)
  • Angiotensin II (1-7) heptapeptide
  • GTPL582
  • BDBM85556
  • AS-76407
  • HY-12403
  • 8-Des-phe-angiotensin II
  • IJ3FUK8MOF
  • F85068
  • (S)-1-((6S,9S,12S,15S,18S)-18-((1H-imidazol-4-yl)methyl)-1-amino-6-((S)-2-amino-3-carboxypropanamido)-15-sec-butyl-12-(4-hydroxybenzyl)-1-imino-9-isopropyl-7,10,13,16-tetraoxo-2,8,11,14,17-pentaazanonadecane)pyrrolidine-2-carboxylic acid
  • Angiotensin II, des-phenylalanine(8)-
  • AKOS040759110
  • TXA127
  • Angiotensin (1-7) acetate salt hydrate
  • Ang-1-7 acetate
  • Angiotensin, Canine, Rat
  • L-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-proline
  • GTPL5578
  • Human angiotensin-(1-7)
  • [125I]angiotensin-(1-7) (human, mouse, rat)
  • SCHEMBL15926158
  • Human angiotensin ii (1-7)
  • UNII-IJ3FUK8MOF
  • Angiotensin II, 5-L-isoleucine-8-de-L-phenylalanine-
  • AKOS024456667
  • Bf-angiotensin 1-7
  • CHEMBL3545347
  • MFCD00153513
  • A901408

MDL Number

MFCD00153513

FAQ

What is Angiotensin I (1-7) (CAS: 51833-78-4)?

Angiotensin I (1-7) (CAS: 51833-78-4) is a fragment of the larger angiotensin I peptide. It consists of the first seven amino acids of angiotensin I, which is derived from the conversion of angiotensinogen by renin. This fragment has been studied for its potential biological and pharmacological effects.

What are the main uses of Angiotensin I (1-7) (CAS: 51833-78-4)?

Angiotensin I (1-7) (CAS: 51833-78-4) is primarily used in research for studying the renin-angiotensin system and its role in blood pressure regulation. It is also used as a tool in pharmacological studies to investigate the effects of angiotensin peptides on cardiovascular function.

Is Angiotensin I (1-7) (CAS: 51833-78-4) safe?

Angiotensin I (1-7) (CAS: 51833-78-4) is generally considered safe for research use. However, it should be handled with appropriate protective measures such as gloves and goggles. Ensure proper ventilation and avoid contact with skin and eyes.

How should Angiotensin I (1-7) (CAS: 51833-78-4) be stored?

Angiotensin I (1-7) (CAS: 51833-78-4) should be stored in a cool, dry place, protected from light. It should be kept at temperatures below 25°C and away from heat sources. The compound should be stored in a tightly sealed container to prevent degradation.

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