L-gamma-Glutamylglycine

Basic Information

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CAS Number

1948-29-4

Molecular Formula

C7H12N2O5

Molecular Weight

204.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Boiling Point

586.6°Cat760mmHg

Density

1.424

Flash Point

308.6°C

Refractive Index

1.536

SMILES

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C(CC(=O)NCC(=O)O)C(C(=O)O)N

InChI

InChI=1S/C7H12N2O5/c8-4(7(13)14)1-2-5(10)9-3-6(11)12/h4H,1-3,8H2,(H,9,10)(H,11,12)(H,13,14)/t4-/m0/s1

InChIKey

ACIJGUBIMXQCMF-BYPYZUCNSA-N

LogP

-1.6206999999999985

Topological Polar Surface Area

129.72 Å²

Hydrogen Bond Donor/Acceptor

5 / 7

Complexity

240

Synonyms & References

English

N-L-gamma-glutamyl-Glycine
H-gamma-Glu-Gly-OH
5-[(Carboxymethyl)imino]-5-hydroxynorvaline
H-Glu(Gly-OH)-OH
L-.GAMMA.-GLUTAMYLGLYCINE
SCHEMBL1769055
gamma-Glu-Gly
3KY8AC5IUW
MFCD00037216
N-L-gamma-glutamylglycine
1948-29-4
gamma-L-Glu-Gly
Glycine, N-D-gamma-glutamyl-
MS-23101
gamma-Glutamyl glycine
AKOS030525460
DTXSID90986480
(2S)-2-amino-5-(carboxymethylamino)-5-oxopentanoic acid
??-Glu-Gly
5-L-Glutamyl-glycine
L-gamma-glutamylglycine
L-gamma-Glu-Gly
(2S)-2-amino-4-[(carboxymethyl)carbamoyl]butanoic acid
GLYCINE, L-.GAMMA.-GLUTAMYL-
gamma-L-glutamyl glycine
gamma-L-Glutamyl-glycine
GLUTAMINE, N-(CARBOXYMETHYL)-, L-
CHEBI:73845
HY-P3280
H-
CS-0197872

MDL Number

MFCD00037216

FAQ

What are the physical and chemical properties of L-gamma-Glutamylglycine (CAS: 1948-29-4)?

L-gamma-Glutamylglycine (CAS: 1948-29-4) is a crystalline compound with a molecular weight of approximately 152.17 g/mol. It has a solubility of about 40 mg/mL in water. This compound is relatively stable but can undergo hydrolysis under acidic or alkaline conditions. It is used in pharmaceutical applications and research due to its specific reactivity.

How is L-gamma-Glutamylglycine (CAS: 1948-29-4) typically synthesized?

L-gamma-Glutamylglycine (CAS: 1948-29-4) is typically synthesized through peptide coupling reactions, often using solid-phase synthesis techniques. The process involves coupling 2-aminoglycine with gamma-glutamyl chloride in the presence of a suitable coupling agent like 1-hydroxybenzotriazole (HOBt) and a catalytic amount of a coupling reagent like N,N'-dicyclohexylcarbodiimide (DCC). The yield is generally high, and the product is purified by techniques such as HPLC.

What industries use L-gamma-Glutamylglycine (CAS: 1948-29-4)?

L-gamma-Glutamylglycine (CAS: 1948-29-4) is primarily used in the pharmaceutical industry for the development of specific drugs. It also finds applications in the sensor industry due to its unique chemical properties, which make it suitable for biosensor development. Additionally, it is utilized in research and development for various biological and biochemical studies.

What precautions should be taken when handling L-gamma-Glutamylglycine (CAS: 1948-29-4)?

When handling L-gamma-Glutamylglycine (CAS: 1948-29-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, a lab coat, and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of dust or vapors. Spills should be cleaned up immediately using appropriate absorbents and following the safety data sheet (SDS) guidelines. Always refer to the SDS for specific handling and emergency procedures.