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Bleomycin A5(CAS: 11116-32-8)
CAS Number
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Basic Information
Molecular Formula
C57H89N19O21S2
Molecular Weight
1440.6 g/mol
Chemical Identifiers
SMILES
CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCNCCCCN)O
InChIKey
QYOAUOAXCQAEMW-UTXKDXHTSA-N
Database References
MDL Number
MFCD00869290
FAQ
Bleomycin A5 (CAS: 11116-32-8) is a cyclic polyketide antibiotic with a molecular weight of approximately 1924 g/mol. It is insoluble in water but soluble in organic solvents like ethanol and dimethyl sulfoxide. Chemically, it exhibits oxidative reactivity and is known for its antitumor activity.
Bleomycin A5 (CAS: 11116-32-8) is synthesized through multi-step chemical reactions starting from dihydrostreptochinone. The synthesis involves various steps such as acetylation, epimerization, and cyclization, yielding a high purity product with a high selectivity and yield of about 50%.
Bleomycin A5 (CAS: 11116-32-8) is primarily used in the pharmaceutical industry for its antitumor properties. It is also explored in biotechnology for gene delivery and in medical research for cancer treatment studies.
When handling Bleomycin A5 (CAS: 11116-32-8), it is essential to use personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a well-ventilated fume hood. In case of spill, immediately clean up using appropriate absorbent materials and follow local safety guidelines. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures