CAPREOMYCIN | CAS No. 11003-38-6

CAPREOMYCIN

Basic Information

View in Editor

CAS Number

11003-38-6

Molecular Formula

C50H88N28O15

Molecular Weight

1321.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

O=C1[C@]([H])([C@@]2([H])CCN=C(N)N2)NC(/C(=C\NC(N)=O)/NC([C@H](CNC(C[C@H](CCCN)N)=O)NC([C@H](CO)NC([C@H](CN1)N)=O)=O)=O)=O.O=C1[C@]([H])([C@@]2([H])CCN=C(N)N2)NC(/C(=C\NC(N)=O)/NC([C@H](CNC(C[C@H](CCCN)N)=O)NC([C@H](C)NC([C@H](CN1)N)=O)=O)=O)=O

InChI

InChI=1S/C25H44N14O8.C25H44N14O7/c26-4-1-2-11(27)6-17(41)32-8-14-20(43)35-15(9-34-25(30)47)21(44)39-18(13-3-5-31-24(29)38-13)23(46)33-7-12(28)19(42)37-16(10-40)22(45)36-14;1-11-19(41)36-15(9-32-17(40)7-12(27)3-2-5-26)21(43)37-16(10-34-25(30)46)22(44)39-18(14-4-6-31-24(29)38-14)23(45)33-8-13(28)20(42)35-11/h9,11-14,16,18,40H,1-8,10,26-28H2,(H,32,41)(H,33,46)(H,35,43)(H,36,45)(H,37,42)(H,39,44)(H3,29,31,38)(H3,30,34,47);10-15,18H,2-9,26-28H2,1H3,(H,32,40)(H,33,45)(H,35,42)(H,36,41)(H,37,43)(H,39,44)(H3,29,31,38)(H3,30,34,46)/b15-9+;16-10+/t11-,12-,13+,14-,16-,18-;11-,12-,13-,14+,15-,18-/m00/s1

InChIKey

VCOPTHOUUNAYKQ-WBTCAYNUSA-N

LogP

-15.441999999999892

pKa

pKa in 66% aq DMF: 6.2, 8.2, 10.1, 13.3(at 25℃)

Topological Polar Surface Area

736.6099999999999 Å²

Hydrogen Bond Donor/Acceptor

37 / 43

Synonyms & References

English

CAPREOMYCIN
capastat
capostatin
capromycin
kapreomycin
(3S)-3,6-diamino-N-{[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentaazacyclohexadecan-5-yl]methyl}hexanamide -
Capreomicina
Capreomicina [INN-Spanish]
Capreomycine
Capreomycine [INN-French]
Capreomycinum
Capreomycinum [INN-Latin]
Caprolin
HSDB 3211
UNII-232HYX66HC
CaproMycin, Caprolin, Capastat, Capostatin, L 29275

FAQ

What is Capreomycin (CAS: 11003-38-6)?

Capreomycin (CAS: 11003-38-6) is an aminoglycoside antibiotic used primarily in the treatment of tuberculosis and certain drug-resistant infections. It is composed of a complex mixture of amide and alcohol derivatives of glucose and glucosamine.

What are the main uses of Capreomycin (CAS: 11003-38-6)?

Capreomycin (CAS: 11003-38-6) is mainly used for treating multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB). It is also used in combination with other antibiotics to treat various resistant bacterial infections.

Is Capreomycin (CAS: 11003-38-6) safe?

Capreomycin (CAS: 11003-38-6) has potential side effects, including ototoxicity and nephrotoxicity. It should be administered under strict medical supervision, and patients should be monitored regularly for kidney function and hearing. Protective measures include proper dosing and avoiding exposure to high levels of the compound.

How should Capreomycin (CAS: 11003-38-6) be stored?

Capreomycin (CAS: 11003-38-6) should be stored in a tightly closed container, protected from light and moisture. It should be kept at a temperature not exceeding 25°C and away from heat sources. The storage area should be secure to prevent unauthorized access and ensure its stability and safety.