Compound Q&A

How is Bleomycin A5 (CAS: 11116-32-8) typically synthesized?

Answer

Bleomycin A5
Bleomycin A5 (CAS: 11116-32-8) is synthesized through multi-step chemical reactions starting from dihydrostreptochinone. The synthesis involves various steps such as acetylation, epimerization, and cyclization, yielding a high purity product with a high selectivity and yield of about 50%.

About

CAS No 11116-32-8
English Name Bleomycin A5
Molecular Formula C57H89N19O21S2
Molecular Weight 1440.6 g/mol
SMILES CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCNCCCCN)O
InChIKey QYOAUOAXCQAEMW-UTXKDXHTSA-N
Last Updated: 2026-03-29 08:05

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