Photoredox-catalyzed difunctionalization of alkenes with oxime esters and NH-sulfoximines
Literature Information
Hao-Cong Li, Guan-Nan Li, Hao-Sen Wang, Xiao-Lan Chen, Bing Yu
A visible-light-induced one-pot three-component reaction of cycloketone oxime esters, NH-sulfoximines, and alkenes was developed for the difunctionalization of alkenes. As a result, a series of versatile sulfoximido-cyanoalkylative products were synthesized under mild and sustainable reaction conditions (up to 98% yield). The significance of this protocol was highlighted by excellent regioselectivity, broad substrate scope, and excellent synthetic applications.
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Organic Chemistry Frontiers

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry












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