N1,N1-Bis(4-aminophenyl)benzene-1,4-diamine trihydrochloride
CAS Number:
114254-48-7
Molecular Formula:
C18H21Cl3N4
A novel three-component coupling reaction of aryne, CN derivatives, and acrylonitrile
Literature Information
Publication Date
2023-11-13
DOI
10.1039/D3QO01454A
Impact Factor
5.281
Authors
Yangang Wu, Wenbo Cai, Lulu Yu, Junbiao Chang, Chuanjun Song
View Original
Abstract
A literature-unprecedented three-component aryne coupling reaction with pyrroline, imine, dihydroisoquinoline, imidazoline or oxazoline as a nucleophile, and acrylonitrile as a third component, acting as both a proton donor and a nucleophile, has been developed. With imidazoline or oxazoline as the substrate, the initially formed three-component reaction product could react further to provide tetrahydro-1,4-diazepine or tetrahydro-1,4-oxazepine, respectively.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
![4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione structure](https://static.chemtradehub.com/structs/209/2093416-31-8-3162.webp "4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione structure")
4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
CAS Number:
2093416-31-8
Molecular Formula:
C21H28N4O7
1-(3,4-Dichlorophenyl)-1H-pyrazole-3-carboxylic acid
CAS Number:
1152949-12-6
Molecular Formula:
C10H6Cl2N2O2
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